Influenza h1n1 fisiopatologia pdf

The pandemic influenza a h1n1 2009 virus was confirmed in all deceased patients. Pdf influenza is an infectious respiratory disease that, in humans, is caused by influenza a and influenza b viruses. Information for pharmacists including information related to supply of antiviral drugs nov 25. Background in late march 2009, an outbreak of a respiratory illness later proved to be caused by novel swineorigin influenza a h1n1 virus soiv was identified in. Influenza diagnosis clinical and epidemiological characteristics increase of febrile respiratory illness lab isolation of influenza virus from clinical specimen e. In the united states, it was first identified in military personnel in spring 1918. Influenza a h1n1 2009 monovalent vaccine is an inactivated influenza virus vaccine indicated for active immunization of persons ages 6 months and older against influenza. The 1918 influenza pandemic was the most severe pandemic in recent history. A, b, c, and only types a and b are perceived to be clinically relevant in humans. Apr 07, 2018 influenza y pandemias textbook of influenza edited by robert g. Crossreactive antibody responses to the 2009 pandemic h1n1 influenza virus external icon. Pneumonia and respiratory failure from swineorigin. Influenza flu is an acute contagious viral infection characterized by inflammation of the respiratory tract that every winter affects more than 100 million people in europe, japan and the united states of america, also being responsible for several thousand of excess deaths data from the united states reveal between 20,000 to 40,000 excess deaths annually. Three main subtypes of swine influenza virus h1n1, h3n2, and h1n2, with h1n1 as the predominant subtype, have circulated in pigs worldwide 2, 3.

Webmd gives frank answers to questions about what we know, and dont know, about the pandemic flu vaccine. The mixovirus influenzae is the agent that causes influenza, commonly called flu. Technically, the term swine flu refers to influenza in pigs. Pandemic influenza h1n1 and mycobacterium tuberculosis coinfection article pdf available in tuberculosis and respiratory diseases 762. The 20172018 influenza a h1n1 vaccine strain differs from that. Investigation of pathogenesis of h1n1 influenza virus and. Swine flu h1n1 flu symptoms and causes mayo clinic. This work is licensed under a creative commons attribution.

First, as the majority of human population has little or no preexisting immunity to the virus, the impact of the infection has been in a wider age. The pandemic h1n1 2009 influenza virus differs in its pathogenicity from seasonal influenza in two key aspects. Less often, someone infected with swine flu passes the infection to others. Gripe influenza fisiopatologia respiratoria youtube. Antigenic and genetic characteristics of swineorigin 2009 a h1n1 influenza viruses circulating in humans pdf icon 327 mb, 7 pages external icon. Although there is not universal consensus regarding where the virus originated, it spread worldwide during 19181919.

In the spring of 2009, scientists recognized a particular strain of flu virus known as h1n1. Clinical aspects of pandemic 2009 influenza a h1n1 virus. Nov 09, 2018 active immunization of persons ages 6 months and older against influenza disease caused by pandemic h1n1 2009 virus. Due to the segmented nature of its genetic material, the influenza virus is highly mutagenic. During the spring of 2009, a novel influenza a h1n1 virus of swine origin caused human infection and acute respiratory illness in mexico. Clinical management of human infection with pandemic h1n1. It is an orthomyxovirus that contains the glycoproteins haemagglutinin and neuraminidase. Emergency use authorization eua of medical products and devices including antiviral drugs. Occasionally, pigs transmit influenza viruses to people, mainly to hog farmers and veterinarians.

An update about the virology and immunology of the influenza a h1n1 infection is. Influenza a h1n1 2009 monovalent vaccine csl limited. Influenza ah1n1 tambien conocida como influenza porcina o gripe del cerdo. Jul 19, 2010 the current influenza a h1n1 2009 strain is a result of genetic translocation from three different species.

Pathology and pathogenesis of 100 fatal cases in the united states. It was caused by an h1n1 virus with genes of avian origin. Antiviral drugs for the 20092010 influenza season oct 19. Influenza is a highly contagious acute viral infection of the respiratory tract. Swine influenza is a highly infectious acute respiratory viral disease of pigs that affects the respiratory tract and has considerable economic impacts. Influenza a virus subtype h1n1 a h1n1 is the subtype of influenza a virus that was the most common cause of human influenza flu in 2009, and is associated with the 1918 outbreak known as the spanish flu. The hospitalisation rate during the 20092010 season was 5.